Research

Publications and White Papers

A First-of-Its-Kind Drug for Concussion Protection

Astrocyte Pharmaceuticals Announces Milestones in the Fight Against Concussions: Launch of Phase 2 Clinical Trial and New $3M NIH Grant

First Human Phase 2 Trial Now Underway

Phase 2 STARFAST (Study of TBI/concussions in Australian-Rules Footballers receiving AST-004)

Green Light for Phase 2 Trial of AST-004 in Acute Ischemic Stroke Patients

Astrocyte Pharmaceuticals Announces FDA Clearance of its Investigational New Drug Application for AST-004

Phase 2 Clinical Trial

Astrocyte Pharmaceuticals Inc., a clinical-stage biopharmaceutical company committed to advancing cerebroprotective therapies.

Jacquin AE, Bazarian JJ, Casa DJ, et al.

Concussion Assessment Potentially Aided by use of an Objective Multimodal Concussion Index.

J Concussion.

2021;5 1–12 http://dx.doi.org/10.1177/20597002211004333

Cathra Halabi , Lynda Norton, Kevin Norton, Wade S. Smith.

Headpulse Recovery in Recently Concussed Young Adult Athletes in Australian Football.

JAMA Network Open.

2023; 6(8):e2328633. 10.1001/jamanetworkopen.2023.28633

Bazarian J, Elbin R, Casa D, Hotz G, Neville C, Lopez R, Schnyer D, Yeargin S, Covassin T.

Validation of a Machine Learning Brain Electrical Activity-Based Index to Aid in Diagnosing Concussion Among Athletes.

JAMA Network Open.

2021;4(2) e2037349. doi:10.1001/jamanetworkopen.2020.37349

A First-of-Its-Kind Drug for Concussion Protection

Astrocyte Pharmaceuticals Announces Milestones in the Fight Against Concussions: Launch of Phase 2 Clinical Trial and New $3M NIH Grant

First Human Phase 2 Trial Now Underway

Phase 2 STARFAST (Study of TBI/concussions in Australian-Rules Footballers receiving AST-004)

Green Light for Phase 2 Trial of AST-004 in Acute Ischemic Stroke Patients

Astrocyte Pharmaceuticals Announces FDA Clearance of its Investigational New Drug Application for AST-004

Phase 2 Clinical Trial

Astrocyte Pharmaceuticals Inc., a clinical-stage biopharmaceutical company committed to advancing cerebroprotective therapies.

A First-of-Its-Kind Drug for Concussion Protection

Astrocyte Pharmaceuticals Announces Milestones in the Fight Against Concussions: Launch of Phase 2 Clinical Trial and New $3M NIH Grant

First Human Phase 2 Trial Now Underway

Phase 2 STARFAST (Study of TBI/concussions in Australian-Rules Footballers receiving AST-004)

Bazarian J, Elbin R, Casa D, Hotz G, Neville C, Lopez R, Schnyer D, Yeargin S, Covassin T.

Validation of a Machine Learning Brain Electrical Activity-Based Index to Aid in Diagnosing Concussion Among Athletes.

JAMA Network Open.

2021;4(2) e2037349. doi:10.1001/jamanetworkopen.2020.37349

Cathra Halabi , Lynda Norton, Kevin Norton, Wade S. Smith.

Headpulse Recovery in Recently Concussed Young Adult Athletes in Australian Football.

JAMA Network Open.

2023; 6(8):e2328633. 10.1001/jamanetworkopen.2023.28633

Jacquin AE, Bazarian JJ, Casa DJ, et al.

Concussion Assessment Potentially Aided by use of an Objective Multimodal Concussion Index.

J Concussion.

2021;5 1–12 http://dx.doi.org/10.1177/20597002211004333

Jacquin A, Kanakia S, Oberly D, Prichep L.

A multimodal biomarker for concussion identification, prognosis and management.

Computers in Biology and Medicine.

2018; 102:95-103. DOI: 10.1016/j.compbiomed.2018.09.011

Wilde EA, Goodrich-Hunsaker MJ, Ware AL, Taylor BA, Biekman BD, Hunter JV, Newman-Norlund R, Scarneo S, Casa DJ, Levin HS.

Diffusion Tensor Imaging Indicators of White Matter Injury Are Correlated with a Multimodal Electroencephalography-Based Biomarker in Slow Recovering, Concussed Collegiate Athletes.

Journal Neurotrauma.

2020; doi.org/10.1089/neu.2018.6365

Covassin T, McGowan AL, Bretzin AC, Anderson M, Petit KM, Savage JL, Stephenson KL, Elbin RJ, Pontifex MB.

Preliminary investigation of a multimodal enhanced brain function index among high school and collegiate concussed male and female athletes.

The Physician and Sportsmedicine.

2020; do: 10.1080/00913847.2020.1745717.

Barr W, Prichep L, Chabot R, Powell M, McCrea M.

Measuring Brain Electrical Activity to Track Recovery from Sport Related Concussion.

Brain Injury.

2012; 26(1):58-66. DOI: doi.org/10.3109/02699052.2011.608216

McCrea M, Prichep L, Powell M, Chabot R, Barr W.

Acute Effects and Recovery After Sports-Related Concussion: A Neurocognitive and Quantitative Brain Electrical Activity Study.

Journal of Head Trauma Rehabilitation.

2010; 25(4):283-292. DOI: 10.1097/HTR.0b013e3181e67923

Brooks MA, Bazarian JJ, Prichep LS, Ghosh-Dastidar S, Talavage TM, Barr W.

The Use of an Electrophysiological Brain Function Index in the Evaluation of Concussed Athletes.

Journal of Head Trauma Rehabilitation.

2018; 33(1):1-6. DOI: 10.1097/HTR.0000000000000328

Prichep L, McCrea M, Barr W, Powell M, Chabot R.

Time Course of Clinical and Electrophysiological Recovery After Sport-Related Concussion.

Journal of Head Trauma Rehabilitation.

2013; 28(4):266-273. DOI: 10.1097/HTR.0b013e318247b54e

Curley KC, O’Neil BJ, Naunheim R, Wright DW.

Intracranial Pathology (CT+) in Emergency Department Patients With High GCS and High Standard Assessment of Concussion (SAC) Scores.

Journal of Head Trauma Rehabilitation.

2018; 33(3):E61-E66. doi: 10.1097/HTR.0000000000000355

Wilder, J.

Multimodal Assessment of Sports Concussion Using BrainScope One.

White Paper

2018

Prichep, L.

BrainScope EEG Capabilities.

White Paper

2020