Past Clinical Trials

Harnessing the power of world class science and research.

Australian Trials

Sport and Real Knowledge P/L (Spark) is dedicated to helping solve the concussion in sport problem.

2021-2022 Clinical Trials

In 2021/22 Spark collaborated with the University of California, San Francisco (UCSF) to test the effectiveness of a novel non invasive medical device designed to objectively detect and measure concussion.

The specially designed headset used cranial accelerometers to measure alterations to the head pulse following all forms of traumatic brain injury (TBI).

The results of this study were published in 2023, and the device continues to work its way through the US regulatory process.

2023 Clinical Trials

In 2023, Spark conducted a trial to establish and test enhanced concussion care protocols.

With US based bio tech company Brainscope providing world first EEG based technology, 120 local football players provided baseline, game day and ongoing testing of concussed players through their recovery period.

The AI assisted technology is sophisticated and does provide an objective measure of concussion suggesting future opportunities exist in the management of concussion.

Brainscope are currently focussed on establishing their presence in the US market.

2025 Clinical Trials

Spark is collaborating with US based Astrocyte Pharmaceuticals who have developed a breakthrough concussion drug designed to preserve and protect brain function at the cellular level, limiting the short and long term damage that can occur after head impact.

During the 2025 season we successfully launched the STARFAST clinical study with the participation of 13 clubs. The trial enabled us to provide access to a novel neuroprotectant for players who experienced a concussion, supporting enhanced concussion management and player welfare. 

The groundbreaking new study focusses on harnessing the Astrocyte cells unique natural function to protect and repair the brain after injury and will measure expected outcomes of the treatment in impacting players brain biomarkers, symptom recovery and the ability to preserve brain cells during injury.

Community Football Clubs on the Front Line of Concussion

Setting

Participating Clubs

Port Districts
Rostrevor OC
Athelsone
Goodwood Saints
Lobethal
Tea Tree Gully
Adelaide Uni
Old Ignatians
Brighton Bombers
Hope Valley
Old Ignations
Kilburn
Pulteney

Testing

All players are monitored each week with all suspected concussed players medically diagnosed by an independent concussion specialist.

If concussed, the player enters a research facility overnight where the treatment is administered within 6 hours of the injury occurring.

The player is then assessed on days 3, 7, 14 and 21 to assess the players brain biomarkers for symptom recovery and brain cell preservation.

Results

Outcome pending

20

Week trial period

13

Participating Clubs

45

Teams

1300

Players

World class science and research

Player welfare

Every club’s no. 1 priority

The dangers associated with concussion, such as repetitive hits and the likely link to CTE and other long term brain impairment, are becoming more widely recognised and understood.

Follow our progress

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